Wrangling Over Abortion Intensifies 
       As RU-486 Pill Nears the Market
         
            By RACHEL ZIMMERMAN    November 14, 2000 
            Staff Reporter of THE WALL STREET JOURNAL
            This week, Danco Laboratories LLC is expected to begin shipping the 
            first commercial supplies of the early-abortion pill known as RU-486 
            to medical providers.

            The move comes after years of controversy over the drug, 
            mifepristone, to be marketed as Mifeprex. And even as the pill 
            becomes available, it is clear that the wrangling, far from being 
            over, is intensifying.
            Proponents of abortion rights are funding 
            projects to boost access to the drug regimen. Opponents, meanwhile, 
            are barraging doctors with mail noting potential hazards.
            And after weeks of tense negotiations over the price of the pills, 
            Danco has decided to charge $270 for the three-pill regimen, 
            according to people close to the negotiations. That cost excludes 
            the price of another drug, misoprostol, needed to complete the 
            abortion, as well as a doctor's charge, counseling and other fees, 
            and is prompting criticism that the bill for doing a so-called 
            medical abortion is way too high.

            "I wish the price was more affordable," says Vicki Saporta, 
            executive director of the National Abortion Federation.
            Ms. Saporta says that her organization has been negotiating a lower 
            price for nonprofit abortion clinics. She adds that the federation 
            helped lobby Danco, which was formed to market Mifeprex, to reduce 
            the minimum purchase requirement of $3,000 the company initially 
            proposed. Danco wouldn't comment on the dispute. The company did say 
            that Medicare reimbursements and other insurance coverage are still 
            being negotiated.

            Mifeprex will only be dispensed by doctors, hospitals and clinics, 
            not by pharmacies. As a result, the network of providers will be 
            limited at first to doctors and clinics that already provide 
            surgical abortions, which generally range in price from $300-$700. 
            But the number of those who can provide a medical abortion should 
            swell to hundreds more within the coming months. That's because 
            several deep-pocketed organizations are backing projects to boost 
            access.

            For example, the Open Society Institute, the New York-based 
            nonprofit funded by financier George Soros, is finalizing plans to 
            give about $1 million to Planned Parenthood Federation of America 
            early next year.

            The Soros money is to support a "Nationwide Mifepristone 
            Affiliate-Readiness Project" that, among other things, will buy 300 
            ultrasound machines for fetal examination and pay for a nationwide 
            television and magazine advertising campaign that will begin 
            sometime next year.

            Mr. Soros, a longtime supporter of abortion rights, will also give 
            away hundreds of thousands of dollars to other pro-choice 
            organizations, according to Ellen Chesler, who oversees the 
            reproductive-rights program at Mr. Soros's Open Society Institute. 
            For instance, the New York state chapter of the National Abortion 
            and Reproductive Rights Action League is undertaking a program to 
            make medical abortion available to family doctors in rural areas.
            Why? In the U.S, 87% of counties don't have an abortion provider, 
            and studies show the overall number of abortion doctors decreased 
            14% in the 1992-1996 period, due largely to fear of antiabortion 
            violence and intimidation. In Alaska's state capital, Juneau, for 
            instance, there is not a single abortion provider. Callers to the 
            Juneau Coalition for Pro-Choice get a recording that says, in order 
            to get an abortion, "you have to leave Juneau or leave the state."
            Women in northern and western Michigan have to travel 11 hours to 
            the nearest provider, and then wait for 24 hours before getting an 
            abortion; and in many rural areas of Texas, the closest provider is 
            often 300 miles away, says Kelli Conlin, executive director of the 
            New York chapter of the abortion-action league.

            "Mifepristone opens up a much greater pool of potential providers," 
            Ms. Conlin says. "We're hoping that local physicians in these areas 
            will quietly start offering this to their patients."

            The Soros Foundation is also expecting to fund a new program at Long 
            Island College Hospital in Brooklyn to train about 20 primary-care 
            doctors a year who have never performed abortions to incorporate 
            mifepristone-induced abortions into their practices. Overall, most 
            of the grants are seeking to promote a shift in the way abortion is 
            delivered -- away from stand-alone, easy-to-target clinics and 
            toward more integration into mainstream medical care.

            Linda Prine, a family physician in Manhattan who has not previously 
            provided abortions to her patients, is looking forward to 
            incorporating RU486 into her practice.
            "Up until now, if a patient of mine was pregnant and wanted to keep 
            the pregnancy I could take care of her," Dr. Prine says. "If she was 
            pregnant and didn't want to have a baby, I had to send her away and 
            that never felt right. Now I can continue to stay with my patients. 
            If we really believe in the right to choose, we have to practice it. 
            Now, with medical abortion, we can."

            To obtain the package of pills, physicians must fill out a 
            double-sided order form and a prescriber's agreement, available on 
            Danco's Web site and through Planned Parenthood and the National 
            Abortion Federation. Providers send the completed form to a national 
            pharmaceutical distributor, who enters the information into a 
            database and ships the drugs.

            Meantime, the abortion politics that have been so contentious for so 
            many years, are heating up as antiabortion forces step up their 
            efforts against the new pill.

            Life Dynamics, a conservative Christian group in Denton, Texas, 
            known for filing malpractice lawsuits against doctors who perform 
            abortions, has sent 150,000 letters to obstetrician/gynecologists 
            and family-practice physicians warning of possible adverse effects 
            from mifepristone.

            "Physicians who perform chemical abortions will be identified, 
            labeled, exposed, stigmatized, ostracized and in every way treated 
            exactly the same as conventional abortionists," says direct mail 
            from Life Dynamics president, Mark Crutcher.

            A graphic new Web site -- the "RU-486 Registry" -- by antiabortion 
            activist Neal Horsley is up again after being shut down several 
            times. The site promises to list doctors who prescribe mifepristone 
            and in some cases even their children and where they attend school.
            Mr. Horsley has already been banished by three different Internet 
            service providers following alerts from the National Abortion 
            Federation. "Don't think we're discouraged," Mr. Horsley says. 
            "We're prepared to do whatever we can to alert people to the horror 
            created by those who make a living slaughtering unborn babies."

            And then, there's the presidential election. If George W. Bush is 
            declared the winner, an amendment by Republican Rep. Tom Coburn of 
            Oklahoma imposing strong restrictions on mifepristone will likely 
            resurface: Gov. Bush has said he would sign such an amendment.
            The amendment would limit medical abortions by allowing the drug to 
            be prescribed only by doctors already trained to perform surgical 
            abortions and ultrasound exams and who have admitting privileges at 
            a hospital less than an hour away.

            Additionally, Republican Rep. Tom Bliley of Virginia, outgoing 
            chairman of the House Commerce Committee, continues to raise 
            questions about the Food and Drug Administration's September 
            approval of mifepristone, specifically questioning the legitimacy of 
            the Shanghai plant where the drug will be manufactured.
            So far, none of the charges have led to further investigation by the 
            agency. But producing mifepristone at an obscure factory in China is 
            certain to be a cloud of concern hanging over the drug.
            Write to Rachel Zimmerman at rachel.zimmerman@wsj.com